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(rac)-Rivastigmine-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(rac)-Rivastigmine-d6图片
CAS NO:194930-04-6
包装与价格:
包装价格(元)
1mg电议
10mg电议

产品名称
利凡斯的明 d6
产品介绍
(Rac)-Rivastigmine-d6 ((Rac)-Rivastigmine-d6) 是 Rivastigmine 氘代消旋体。Rivastigmine (S-Rivastigmine) 是一种具有口服活性的,有效的胆碱酯酶 (ChE) 抑制剂,可抑制丁酰胆碱酯酶 (BChE) 和乙酰胆碱酯酶 (AChE),IC50分别为 0.037 μM 和 4.15 μM。Rivastigmine 可透过血脑屏障 (BBB)。Rivastigmine 是一种拟副交感神经剂或胆碱能剂,用于研究轻度至中度阿尔茨海默氏型痴呆和帕金森氏病引起的痴呆。
生物活性

(Rac)-Rivastigmine-d6 ((Rac)-Rivastigmine-d6) is a labelled racemic Rivastigmine. Rivastigmine (S-Rivastigmine) is an orally active and potentcholinesterase (ChE)inhibitor and inhibitsbutyrylcholinesterase (BChE)andacetylcholinesteras (AChE)withIC50s of 0.037 μM , 4.15 μM, respectively. Rivastigmine can pass the blood brain barrier (BBB). Rivastigmine is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

256.37

Formula

C14H16D6N2O2

CAS 号

194930-04-6

中文名称

利凡斯的明 d6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.