CAS NO: | 3522-50-7 |
包装 | 价格(元) |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | Ferric citrate (Iron(III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) research[1][2]. | ||||||||||||||||
体外研究 (In Vitro) | Ferric citrate (Iron(III) citrate; 1 mM; 24 hours) significantly induces CM cell death[1]. Cell Viability Assay[1]
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体内研究 (In Vivo) | Here we compared the effects of Ferric citrate (25 μg/g) administration versus a mineral sufficient control diet using the Col4a3 knockout mouse model of progressive CKD and age-matched wild-type mice. Ferric citrate is given to knockout mice for four weeks beginning at six weeks of age when they had overt chronic kidney disease (CKD), or for six weeks beginning at four weeks of age when they had early CKD. Ferric citrate rescues iron deficiency and anemia in knockout mice regardless of the timing of treatment initiation, and circulating levels and bone expression of FGF23 are reduced. Ferric citrate also improves cardiac function and significantly improves survival[3]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 244.94 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C6H5FeO7 | ||||||||||||||||
CAS 号 | 3522-50-7 | ||||||||||||||||
中文名称 | 柠檬酸铁;枸橼酸铁;柠檬酸三铁 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: H2O : 5 mg/mL(20.41 mM;ultrasonic and warming and heat to 60℃) 配制储备液
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以下溶剂前显示的百
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