CAS NO: | 2043660-80-4 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | CPUL1 is aTrxRinhibitor, which shows proliferation-inhibitory and anti-metastatic activity against A549 cells. CPUL1 influences EMT (epithelial-mesenchymal transition) via inducing ROS-mediatedERK/JNKsignaling by inhibiting TrxR1 enzyme activity. CPUL1 in combination withα-Lipoic Acid(HY-N0492) orDithiodipropionic acid(HY-W014395) is more effective[1]. | ||||||||||||||||||||||||
体外研究 (In Vitro) | CPUL1 (2.5, 5, 10, 20, 40 μM; 48 h) inhibits A549 cell proliferation and (2, 4, 8 μM; 48 h) colony formation[1]. Cell Proliferation Assay[1]
Cell Viability Assay[1]
Cell Migration Assay[1]
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分子量 | 434.28 | ||||||||||||||||||||||||
Formula | C22H13Cl2N5O | ||||||||||||||||||||||||
CAS 号 | 2043660-80-4 | ||||||||||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |