11-Azidoundecanoic acid is aclick chemistryreagent containing an azide group. 11-Azidoundecanoic acid acts as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. 11-Azidoundecanoic acid is substrate oflipoic acid ligase(LpIA) for labeling^[1][2].

The microbial lipoic acid ligase (LplA) can specifically attach an alkyl azide onto an engineered LplA acceptor peptide (LAP). Then the alkyl azide selectively derivatizes with cyclooctyne conjugates to various probes^[1].
LplA method should provide general access to biochemical and imaging studies of cell surface proteins, using small fluorophores introduced via a short peptide tag^[1].

227.30

Solid

C₁₁H₂₁N₃O₂

118162-45-1

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)