您好，欢迎来到化工原料网！ [登录] [免费注册]
化工原料网
发布求购
位置：首页 > 产品库 > Drofenine hydrochloride(Hexahydroadiphenine hydrochloride)
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Drofenine hydrochloride(Hexahydroadiphenine hydrochloride)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Drofenine hydrochloride(Hexahydroadiphenine hydrochloride)图片
CAS NO:548-66-3
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
Drofenine hydrochloride (Hexahydroadiphenine hydrochloride) 是一种有效的 BChE 竞争性抑制剂，计算出 Drofenine 的 ki 值为 3 uM。
Cas No.548-66-3
别名盐酸六氢芬宁,Hexahydroadiphenine hydrochloride
Canonical SMILESO=C(OCCN(CC)CC)C(C1CCCCC1)C2=CC=CC=C2.[H]Cl
分子式C20H32ClNO2
分子量353.93
溶解度DMSO : ≥ 75 mg/mL (211.91 mM);Water : ≥ 33.3 mg/mL (94.09 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Drofenine hydrochloride is a potent competitive inhibitor of BChE, and the ki values of Drofenine is calculated to be 3 uM.IC50 value: 3 uM (ki)Target: BChEBenactyzine is widely used anticholinergic drugs, acts on smooth muscle to stop muscle spasms.

[1]. Bodur E, et al. Inhibition effects of benactyzine and drofenine on human serum butyrylcholinesterase. Arch Biochem Biophys. 2001 Feb 1;386(1):25-29.