CAS NO: | 1202884-94-3 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | PI3K-IN-22 is aPI3Kα/mTORdual kinase inhibitor. PI3K-IN-22 hasIC50s of 0.9, 0.6 nM forPI3KαandmTOR, respectively. PI3K-IN-22 can be used for the research ofcancer[1]. | ||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | PI3K-IN-22 (compound 46) inhibits the cell growth of PC3 and MDA-361 cells with IC50s of<3.0 and 13.0 nM[1]. | ||||||||
体内研究 (In Vivo) | PI3K-IN-22 (25 mg/kg; i.v.) suppresses phosphorylation of Akt T308, Akt S473 and S6K in MDA361 breast tumor cells up to 8 h in MDA361 tumor bearing nude mice demonstrated by biomarker studies[1].
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分子量 | 624.66 | ||||||||
Formula | C31H35F3N8O3 | ||||||||
CAS 号 | 1202884-94-3 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |