CAS NO: | 6318-41-8 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | AS-041164 is a potent, selective and orally activePI3Kγisoform inhibitor with anIC50of 70 nM. AS-041164 shows less activity againstPI3Kα,PI3Kβ, andPI3Kδ(IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively). AS-041164 has anti-inflammatory effects[1]. | ||||||||||||||||
IC50& Target[1] |
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体内研究 (In Vivo) | AS-041164 (10-100 mg/kg; oral administration; once) treatment results in the reduction of inflammatory swelling in the model of carrageenan-induced paw edema[1].
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分子量 | 249.24 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C11H7NO4S | ||||||||||||||||
CAS 号 | 6318-41-8 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 125 mg/mL(501.52 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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