(S,R,S)-AHPC-PEG3-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used inPROTACtechnology.

(S,R,S)-AHPC-PEG3-N3 is extracted from patent WO/2016/146985A1, figure 11. PROTAC has been developed having structure A-L-B that can tether a bromodomain inhibitor via a moiety which binds to a protein within the bromo- and Extra-terminal (BET) family of proteins to a small molecule E3 ubiquintin ligase protein binding ligand compond via a suitable linker^[1][2].

645.77

Oil

C₃₀H₄₃N₇O₇S

1797406-80-4

Room temperature in continental US; may vary elsewhere.

Ethanol : 100 mg/mL(154.85 mM;Need ultrasonic)

H₂O : ≥ 100 mg/mL(154.85 mM)

DMSO : 50 mg/mL(77.43 mM;Need ultrasonic)

*"≥" means soluble, but saturation unknown.

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