VHL Ligand-Linker Conjugates 17 包含用于募集 E3 泛素连接酶的 VHL 配体和 linker。VHL Ligand-Linker Conjugates 17 可用于合成一系列 PROTAC 分子，如 ARD-266 (HY-133020)。ARD-266 是一种高效的雄激素受体 (AR) PROTAC 降解剂。
| 生物活性 | VHL Ligand-Linker Conjugates 17 incorporates a VHL ligand for the E3 ubiquitin ligase, and aPROTAClinker. VHL Ligand-Linker Conjugates 17 can be used in the synthesis of a series ofPROTACs, such as ARD-266 (HY-133020). ARD-266 is a highly potentandrogen receptor(AR)PROTACdegrader[1]. |
| IC50& Target[1] | |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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