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Thalidomide-O-amido-C8-NH2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Thalidomide-O-amido-C8-NH2图片
CAS NO:1950635-15-0
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
Cereblon Ligand-Linker Conjugates 2
E3 Ligase Ligand-Linker Conjugates 20
产品介绍
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2) 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。可用于合成 PROTAC 分子。
生物活性

Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide basedcereblonligand and a linker, can be used in the synthesis ofPROTACs[1].

IC50& Target[1]

Cereblon

 

体外研究
(In Vitro)

Thalidomide-O-amido-C8-NH2 is a degron-linker (refer to Compound DL7-TL). ThePROTAClinker is bound lo at least one targeting ligand. Degron-linker-targeting ligand, wherein the linker is covalently bound lo at least one degron and at least one targeting ligand, the degron is a compound capable of binding to an ubiquitin ligase such as an E3 ubiquitin ligase (e g, cereblon), and the targeting ligand is capable of binding to the targeted protein (s)[1].

分子量

458.51

Formula

C23H30N4O6

CAS 号

1950635-15-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.