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Panaxadiol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Panaxadiol图片
CAS NO:19666-76-3
包装:20mg
市场价:420元

产品介绍
Panaxadiol (20(R)-Panaxadiol) 是一种具有口服活性的 HIF-1α/STAT3 抑制剂。 Panaxadiol 可以抑制 HIF-1α 和 STAT3,然后导致程序性细胞死亡配体 1 (PD-L1) 表达的下调。 Panaxadiol 具有抗癌、心脏保护、抗心律失常和抗氧化活性。
Cas No.19666-76-3
别名人参二醇; 20(R)-Panaxadiol
化学名4,4,8,10,14-pentamethyl-17-(2,6,6-trimethyloxan-2-yl)-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,12-diol
Canonical SMILESCC1(CCCC(O1)(C)C2CCC3(C2C(CC4C3(CCC5C4(CCC(C5(C)C)O)C)C)O)C)C
分子式C30H52O3
分子量460.73
溶解度Chloroform: 10 mg/ml,Ethanol: 0.25 mg/ml
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Panaxadiol is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.

References:
[1]. Xiaojun C, et al. An UFLC-MS/MS method for quantification of panaxadiol in rat plasma and its application to a pharmacokinetic study. Planta Med. 2013 Sep;79(14):1324-8.
[2]. Tae-Hoon Kim, et al. The effects of ginseng total saponin, panaxadiol and panaxatriol on ischemia/reperfusion injury in isolated rat heart. Food and Chemical ToxicologyVolume 48, Issue 6, June 2010, Pages 1516–1520