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Abemaciclib metabolite M18-d8
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Abemaciclib metabolite M18-d8图片
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
LSN3106729-d8
产品介绍
Abemaciclib metabolite M18-d8 (LSN3106729-d8) 是 Abemaciclib metabolite M18 的氘代物。Abemaciclib metabolite M18 (LSN3106729),Abemaciclib 的代谢物, 是一种具有抗肿瘤活性的CDK抑制剂。Abemaciclib metabolite M18 和 CRBN 配体可用于设计 PROTAC CDK4/6 降解剂。
生物活性

Abemaciclib metabolite M18-d8 (LSN3106729-d8) is the deuterium labeled Abemaciclib metabolite M18. Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib (HY-16297A), is aCDKinhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to designPROTACCDK4/6 degrader[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

502.59

Formula

C25H20D8F2N8O

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.