| CAS NO: | 134179-38-7 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 500mg | 电议 |
| 1 g | 电议 |
| 5 g | 电议 |
| 10 g | 电议 |
| 生物活性 | Amino-PEG3-C2-Azido is a PEG-basedPROTAClinker can be used in the synthesis of thePARP1degrader iRucaparib-TP3 (HY-130645)[1]. |
| 体外研究 (In Vitro) | Pomalidomide (a CRBN ligand and a known immunomodulatory imide drug (IMiD)) is conjugated to Rucaparib through a tri(ethylene glycol) (PEG3) linker to afford a compound that we designate as iRucaparib-TP3 (IMiD-Rucaparib with a triazole-PEG3 linker). iRucaparib-TP3 induces PARP1 degradation[1]. |
| 分子量 | 218.25 |
| 性状 | Oil |
| Formula | C8H18N4O3 |
| CAS 号 | 134179-38-7 |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | -20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
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