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Biotin-PEG3-azide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Biotin-PEG3-azide图片
CAS NO:875770-34-6
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
Biotin-PEG3-azide 是一种基于 PEG 结构的PROTAC linker,可用于 PROTAC 的合成。
生物活性

Biotin-PEG3-azide is a PEG-basedPROTAClinkercan be used in the synthesis ofPROTACs.

IC50& Target

PEGs

 

体外研究
(In Vitro)

Biotin-C2-PEG3-azide is a biotin with the azide tag, it can be conjugated to antiviral inhibitors, for example, RYL-634, which shows excellent broad-spectrum inhibition activity against various pathogenic viruses, including hepatitis C virus, dengue virus, Zika virus, chikungunya virus, enterovirus[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

分子量

444.55

性状

Solid

Formula

C18H32N6O5S

CAS 号

875770-34-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month