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Boc-11-aminoundecanoic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Boc-11-aminoundecanoic acid图片
CAS NO:10436-25-6
包装与价格:
包装价格(元)
100mg电议
500mg电议
1 g电议
5 g电议
10 g电议

产品介绍
Boc-11-aminoundecanoic acid 是基于 Alkyl/ether 结构的 PROTAC linker, 可以用来制备 MS432 (HY-130602)。
生物活性

Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAClinker can be used in the synthesis of MS432 (HY-130602)[1].

IC50& Target

Alkyl/ether

 

体外研究
(In Vitro)

MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

分子量

301.42

性状

Solid

Formula

C16H31NO4

CAS 号

10436-25-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month