蛋白质/抗原/多肽 >> 重组蛋白
重组干扰素诱导蛋白44样蛋白
产品介绍 基因名: IFI44L 产品别名: C1orf29; GS3686; TLDC5B; IFI44L; interferon induced protein 44 like; interferon induced protein 44 like; interferon-induced protein 44-like; 干扰素诱导蛋白44样蛋白; 背景信息: IFI-44L is a 452 amino acid cytoplasmic protein that shares some sequence similarities with IFI-44. IFI-44 is a cytoplasmic protein that aggregates to form microtubule structures. The genes that encode IFI-44L and IFI-44 are located on chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. 标签:His-tag |
相关产品
|