蛋白质/抗原/多肽 >> 重组蛋白
重组肽基精氨酸脱亚氨酶Ⅰ(PADI1)蛋白
产品介绍 基因名: Padi1 产品别名: AV236283; Pdi1; Padi1; peptidyl arginine deiminase, type I; peptidyl arginine deiminase, type I; protein-arginine deiminase type-1; PAD type I; PROTEIN-ARGININE DEIMINASE TYPE I (PEPTIDYLARGININE DEIMINASE I); Pad type 1; peptidylarginine deiminase I; 肽基精氨酸脱亚氨酶Ⅰ(PADI1); 蛋白质精氨酸亚型1; 背景信息: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] 标签:His-tag |
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