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蛋白质/抗原/多肽 >> 重组蛋白
重组卷曲螺旋结构域蛋白39
重组卷曲螺旋结构域蛋白39图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant Ccdc39
Recombinant coiled-coil domain containing 39 protein
产品介绍
基因名:

Ccdc39


产品别名:

4921507O14Rik; AI447426; AI844750; D3Ertd789e; b2b1304Clo; b2b1735Clo; b2b2025.1Clo; prh; Ccdc39; coiled-coil domain containing 39; coiled-coil domain containing 39; coiled-coil domain-containing protein 39; 卷曲螺旋结构域蛋白39;


背景信息:
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly.
Tissue specificity:Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.
Involvement in disease:
Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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