产品介绍 基因名: SLCO1C1 产品别名: OATP-F; OATP1; OATP14; OATP1C1; OATPF; OATPRP5; SLC21A14; SLCO1C1; solute carrier organic anion transporter family member 1C1; solute carrier organic anion transporter family member 1C1; solute carrier organic anion transporter family member 1C1; OAT-RP-5; OATP-14; organic anion transporter F; organic anion transporter polypeptide-related protein 5; organic anion transporting polypeptide 14; solute carrier family 21 (organic anion transporter), member 14; solute carrier family 21 member 14; thyroxine transporter; 溶质载体家族蛋白21成员1C1; 背景信息: The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP-F is a 712 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP-F mediates the Na+-independent, high affinity transport of the thyroid hormones thyroxine (T4) and rT3 and other organic anions. OATP-F is also thought to transport estrone-3-sulfate and sulfobromophthalein (BSP), triiodothyronine (T3) and 17-beta-glucuronosyl estradiol at a much lower efficiency. OATP-F is expressed highly in Leydig cells in testis and in brain. 标签:His-tag |
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