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蛋白质/抗原/多肽 >> 重组蛋白
重组信号调节蛋白β2/SIRP-β2
重组信号调节蛋白β2/SIRP-β2图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant SIRPB2
Recombinant signal regulatory protein beta 2 protein
产品介绍
基因名:

SIRPB2


产品别名:

PTPN1L; PTPNS1L3; dJ776F14.2; SIRPB2; signal regulatory protein beta 2; signal regulatory protein beta 2; signal-regulatory protein beta-2; SIRP-beta-2; protein tyrosine phosphatase non-receptor type substrate protein; protein tyrosine phosphatase, non-receptor type substrate 1-like 3; 信号调节蛋白β2/SIRP-β2;


背景信息:
Signal-regulatory protein beta-2(SIRP-beta-2), is a monomeric single pass type I membrane glycoprotein, belongs to the SIRP/SHPS (CD172) family of the immunoglobulin (Ig) superfamily. The SIRP family are paired receptors that have similar extracellular domains but differing C-terminal domains and functions. A positively charged residue within the transmembrane domain, in analogy to SIRP-beta-1, is implicated to mediate interaction with the adaptor DAP12 protein, which contains immunoreceptor tyrosine-based activation motifs (ITAMs) . Proteins in the SIRP family are typically expressed in immune cells, especially in the myeloid lineages . Based on expression patterns, SIRPs are thought to have roles in immune regulation. SIRP family members role in innate immunity and host defense has potential significance as a therapeutic target in cancer and inflammation. There are currently no known mouse or rat homologs for this protein.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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